William Todd Penberthy, Ph. D.
Mobile: (689) 247-0254 • Email: WTPENBER@GMAIL.COM • Website: WWW.CMESCRIBE.COM
With a PhD in Biochemistry, I specialize in medical and scientific writing and communications over the past 8 years focused on medical writing for the biomedical and pharmaceutical industry (since 2012); I have over 16 years’ experience in the scientific field.
I have been the principal writer for a variety of research topics and for studies across many therapeutic areas. These projects have included: interviews with key opinion leaders; medical technology directory reports; Needs Assessments; CME course development (including grant applications, Q&A with data accumulation and slide sets); professional manuscript, abstract and grant writing (federal and private funding); medical and scientific conference coverage; clinical overviews; CSRs, IBs, and patient narratives.
As a researcher, I have established and directed drug discovery collaborations with industry, collaborated with clinicians and researchers, directed a core facility, mentored graduate students, and trained laboratory technicians. I have also been a panel member for drug development, been an invited speaker at research hospitals and at national/international meetings, taught college- and graduate-level courses, and have been an invited journal reviewer as well as primary author of scientifically reviewed manuscripts and textbook chapters for the medical community.
Therapeutic areas: Bone / Osteoporosis, Cardiovascular, CNS, Dermatology, Diabetes, Endocrinology, Hematology, Immunology, Inflammation, Metabolic Disease, Neurology, Oncology, Orthopedics, Respiratory, Rheumatology
Scientific research: Autoimmune Diseases, Biomarkers, Cardiovascular, CNS, Drug Discovery, Hematology, Immunology, Metabolism, Neurology, Nutrition, Oncology
From 2012 to Current: Principal writer CMEScribe LLC
Provide scientific and medical writing consulting services to clients.
• Multiple manuscript writing and research for a biotech company focused on therapeutics in 8 clinical trials currently that are focused on amyotrophic lateral sclerosis, multiple sclerosis, and Parkinson’s Disease
• Clinical study reports, clinical evaluation report, and investigator brochures
• Regular contributor to BioWorld for 18mos and running
• Medical technology directory reports: Comprehensive reviews focused on cutting edge medical technologies for practice, budgetary and policy decisions. Subscription only (see https://www.hayesinc.com/hayes/publications/medical-technology-directory/).
• CME course development, CME credit grant applications, Q&A with data accumulation, slide sets (PowerPoint, Keynote)
• Needs Assessments: diabetes, systemic lupus erythematosus, pediatric multiple sclerosis, schizophrenia, insomnia disorders, generalized tonic-clonic seizures, cystic fibrosis
• Textbook chapters:
• Present Knowledge in Nutrition, Niacin and Biotin, 10th and 11th eds.; 2020 & 2012
• Biochemical, Physiological, and Molecular Aspects of Human Nutrition, Niacin, Riboflavin, and Thiamin, 3rd and 4th eds.; 2019 & 2012
• Professional manuscript, abstract, grant writing for both private and federal funding
• Conference coverage: AAP 2018; ADA 2018; WAC 2018 (AAAAI/WAO); ASM Microbe 2017; ENDO 2017; AAES 2017; HFS 2016; ITC 2015; World Congress on Breast Healthcare 2015; IBD 2020 (2014); ACP 2014; NAMCP 2014; SCAI 2013; CMSC/ACTRIMS 2013
• Physician clinical overviews: Raynaud’s phenomena, B-cell lymphoma, Carcinoid, Desmoid tumors, Hyperleukocytosis in malignancy, Malignant brain tumors in children
• Patient narratives
From 2009-2012, Research Professor, University of Central Florida, Orlando, FL
From 2004-2009, Research Professor, University of Cincinnati, Cincinnati, OH
From 1999 to 2003, Post-doctoral Fellow, UCLA (Los Angeles, CA) and Tufts University (Boston, MA)
• American Medical Writers Association (AMWA)
• American Association for the Advancement of Science (AAAS)
• Global Alliance of Publication Professionals (GAPP)
GRANTS & HONORS
• 2010 Gates Award: Reawakening Retrocyclin as a Potential AIDS Therapeutic
• 2009 Invited speaker, Mayo Clinic Dept. of Anesthesiology, host Dr. Eduardo Nunes Chini
• 2009 Grant reviewer, National Science Foundation
• 2008 Invited speaker, 4th Annual Metabolic Diseases World Summit, Boston, MA.
• 2008 Invited participant, Case Western Univ. School of Medicine, Transdisciplinary Research on Energetics and Cancer (TREC)
• 2008 Invited Participant Discussion: PARP-1 Inhibitors for Glioma, Breast, & Ovarian Cancer
• 2005 R21. Secondhand Smoke and Cardiovascular Disease in Zebrafish, R21ES01817
• 2008 Executive Editor, Current Pharmaceutical Design: Nicotinamide Adenine Dinucleotide Biology and Disease
• 2008 Nominated Honorary Editorial Board of The Journal of International Tryptophan Research
• 2007 Nominated to Marquis Who’s Who in America
• 2004-2007 Biomedical Research Technology Transfer Award BRTT. $120,000/yr
• 2004-2007 Genome Science Millennium Fund
• 2000-2003 F32, Individual National Research Service Award. Neuronal and Hematopoietic Gene Regulation of GATA-2. NIH F32HD401940.
• 1999-2000 Post-doctoral Training Grant. Pathobiology of Digestive Diseases. NIH NIDDK DK07542.
PRESENTATIONS & MEETINGS
• Invited presentation, Mayo Clinic, May 2009, “NAD-Centric Pharmacologic Approaches & Obesity/ COPD Animal Modeling Using Zebrafish”
• Invited presentation and Travel Award, 4th Annual Metabolic Diseases World Summit, Boston, MA 2008: “A high throughput live transparent animal bioassay to identify non-toxic small molecules or genes that regulate vertebrate fat metabolism for obesity drug development”
•. Invited panelist, PARP-1 inhibitors for use in melanoma, ovarian cancer, and glioma; Panel Intelligence, LLC
• Invited speaker, Case Western TREC Retreat 2008, “NAD Pharmacotherapeutics: Zebrafish-based Small Molecule Studies of Lipid Metabolism with Implications for Cancer and Multiple Sclerosis”
• Invited presentation and Travel Award, PARP 2008, Tucson, AZ
• Invited speaker, Dept. of Human Nutrition at Ohio State University: “The Zebrafish Genetic Model Organism for Studying Nutrient Function,” Oct. 2007, Columbus, OH
• Third Annual Ohio Valley Affiliates for Life Sciences, March 7-8, 2007
• Jones, Kevin S., W. Todd Penberthy. 2006. Poster: “NAD Precursors Prevent Chemically-Elicited Neurodegeneration in Zebrafish Larvae.” East Coast PARP Meeting 2006, Quebec City, Quebec, Canada.
• 7th International Conference on Zebrafish Development and Genetics, June 14-16, 2006, Madison, WI
• Lin, Shuo and W. Todd Penberthy. 2005. Poster: “Whole-animal Chromatin Immunoprecipitation Using Zebrafish Embryos”. Strategic Conference of Zebrafish Investigators. Principle investigators only and by invitation, Bar Harbor, ME
• W. Todd Penberthy, Jason R. Jessen, Zhongan Yang, & Shuo Lin. 2002. Oral Presentation: “A Role for BarHl1 in the Regulation of GATA-2 Neural Expression”. The 6th International Conference on Zebrafish Development and Genetics, Madison, WI
SELECTED PUBLICATIONS (from 2009 to present, only)
• Submissions for a major biotechnology company: Biomaterials, British Medical Journal, and Nanomedicine, (2020)
• Penberthy, W. Todd and James B. Kirkland. Niacin (2020) in Present Knowledge in Nutrition. 11th ed., Elsevier, St. Louis, Mo. Edited by Diane Birt and Allison Worden.
• Penberthy, W. Todd, Mahrou Sadri and Janos Zempleni. Biotin (2020) in Present Knowledge in Nutrition. 11th ed., Elsevier, St. Louis, Mo. Edited by Diane Birt and Allison Worden.
• Penberthy, W. Todd. Niacin, Riboflavin, and Thiamine (2019) in Biochemical, Physiological, and Molecular Aspects of Human Nutrition. 4th ed., Elsevier, St. Louis, Mo. Edited by Marie A. Caudill and Martha H. Stipanuk.
• Hu, L, K. Ibrahim, M. Stucki, M. Frapolli, N. Shahbeck, F. A. Chaudhry, B. Gorg, D. Haussinger, W. Todd Penberthy, T. Ben-Omran, and J. Haberle (2015). Secondary NAD+ Deficiency in the Inherited Defect of Glutamine Synthase. Journal of Inherited Metabolic Disease. 38(6):1075-83.
• W. Todd Penberthy & Robert Smith (2015). The Vitamin Cure for Arthritis. A book for laypersons about nutritional approaches to treating arthritis. p1-237.
• Penberthy, W. Todd and James B. Kirkland. Niacin (2012) in Present Knowledge in Nutrition. 10th ed., Elsevier, St. Louis, Mo. Edited by Diane Birt.
• Penberthy, W. Todd. Niacin, Riboflavin, and Thiamine (2012) in Biochemical, Physiological, and Molecular Aspects of Human Nutrition. 3rd ed., Elsevier, St. Louis, Mo. Edited by John W. Erdman and Ian Macdonald.
• Penberthy, W. Todd, Soumya C. Chari, Amy Cole, Alexander Cole (2010). Retrocyclins and Activity against HIV-1. Cellular and Molecular Life Sciences 68(13): 2231-2242.
• Babak Baban, W. Todd Penberthy & Mahmood S. Mozaffari (2010). The Potential Role of Indoleamine 2,3 Dioxygenase (IDO) as a Predictive and Therapeutic Target for Diabetes Treatment: a Mythical Truth; EPMA Journal 1:46–55.
• Penberthy, W. Todd (2009). Nicotinic Acid-Mediated Activation of Both Membrane and Nuclear Receptors Towards Therapeutic Glucocorticoid Mimetics for Potential Treatment of Multiple Sclerosis; PPAR Research 853707-.
• Penberthy, W. Todd (guest executive editor) Current Pharmaceutical Design, 2009. Developed theme, coordinated authors / reviewers, and provided oversight to completion. Theme: NAD Biology in Disease.
• Penberthy, W. Todd & Tsunoda, I. (2009). The Importance of NAD in Multiple Sclerosis. Current Pharmaceutical Design. 2009; 15(1): 64-99.
• Penberthy, W. Todd (2009). Nicotinamide Biology and Disease. Current Pharmaceutical Design;15(1): 1-2.
INVITED JOURNAL REVIEWER
• PPAR Research
• Developmental Dynamics
• Immunology Letters
• Molecular Biology Reports
• Antiviral Research
• Brain Research Bulletin
• Schizophrenia Research
• Journal of Nutrition
• Nucleic Acid Research
• Mutation Research