_{William Todd Penberthy, Ph. D.}

Mobile: (689) 247-0254 • Email: WTPENBER@GMAIL.COM • Website: WWW.CMESCRIBE.COM

 

SUMMARY

With a PhD in Biochemistry, I specialize in medical and scientific writing and communications over the past 8 years focused on medical writing for the biomedical and pharmaceutical industry (since 2012); I have over 16 years’ experience in the scientific field.

I have been the principal writer for a variety of research topics and for studies across many therapeutic areas. These projects have included: interviews with key opinion leaders; medical technology directory reports; Needs Assessments; CME course development (including grant applications, Q&A with data accumulation and slide sets); professional manuscript, abstract and grant writing (federal and private funding); medical and scientific conference coverage; clinical  overviews; CSRs, IBs, and patient narratives.

As a researcher, I have established and directed drug discovery collaborations with industry, collaborated with clinicians and researchers, directed a core facility, mentored graduate students, and trained laboratory technicians. I have also been a panel member for drug development, been an invited speaker at research hospitals and at national/international meetings, taught college- and graduate-level courses, and have been an invited journal reviewer as well as primary author of scientifically reviewed manuscripts and textbook chapters for the medical community.

Therapeutic areas: Bone / Osteoporosis, Cardiovascular, CNS, Dermatology, Diabetes, Endocrinology, Hematology, Immunology, Inflammation, Metabolic Disease, Neurology, Oncology, Orthopedics, Respiratory, Rheumatology

Scientific research: Autoimmune Diseases, Biomarkers, Cardiovascular, CNS, Drug Discovery, Hematology, Immunology, Metabolism, Neurology, Nutrition, Oncology

 

CAREER HISTORY

From 2012 to Current:  Principal writer CMEScribe LLC                      

Provide scientific and medical writing consulting services to clients.

•       Multiple manuscript writing and research for a biotech company focused on therapeutics in 8 clinical trials currently that are focused on amyotrophic lateral sclerosis, multiple sclerosis, and Parkinson’s Disease

•       Clinical study reports, clinical evaluation report, and investigator brochures

•       Regular contributor to BioWorld for 18mos and running

 

•       Medical technology directory reports: Comprehensive reviews focused on cutting edge medical technologies for practice, budgetary and policy decisions. Subscription only (see https://www.hayesinc.com/hayes/publications/medical-technology-directory/).

•       CME course development, CME credit grant applications, Q&A with data accumulation, slide sets (PowerPoint, Keynote)

•       Needs Assessments: diabetes, systemic lupus erythematosus, pediatric multiple sclerosis, schizophrenia, insomnia disorders, generalized tonic-clonic seizures, cystic fibrosis

•       Textbook chapters:

•       Present Knowledge in Nutrition, Niacin and Biotin, 10^th and 11^th eds.; 2020 & 2012

•       Biochemical, Physiological, and Molecular Aspects of Human Nutrition, Niacin, Riboflavin, and Thiamin, 3^rd and 4^th eds.; 2019 & 2012

•       Professional manuscript, abstract, grant writing for both private and federal funding

•       Conference coverage: AAP 2018; ADA 2018; WAC 2018 (AAAAI/WAO); ASM Microbe 2017; ENDO 2017; AAES 2017; HFS 2016; ITC 2015; World Congress on Breast Healthcare 2015; IBD 2020 (2014); ACP 2014; NAMCP 2014; SCAI 2013; CMSC/ACTRIMS 2013

•       Physician clinical overviews: Raynaud’s phenomena, B-cell lymphoma, Carcinoid, Desmoid tumors, Hyperleukocytosis in malignancy, Malignant brain tumors in children

•       Patient narratives

 

From 2009-2012, Research Professor, University of Central Florida, Orlando, FL

From 2004-2009, Research Professor, University of Cincinnati, Cincinnati, OH

From 1999 to 2003, Post-doctoral Fellow, UCLA (Los Angeles, CA) and Tufts University (Boston, MA)

 

PROFESSIONAL ORGANIZATIONS

•                American Medical Writers Association (AMWA)

•                American Association for the Advancement of Science (AAAS)

•                Global Alliance of Publication Professionals (GAPP)

 

GRANTS & HONORS

•                2010 Gates Award: Reawakening Retrocyclin as a Potential AIDS Therapeutic

•                2009 Invited speaker, Mayo Clinic Dept. of Anesthesiology, host Dr. Eduardo Nunes Chini

•                2009 Grant reviewer, National Science Foundation

•                2008 Invited speaker, 4th Annual Metabolic Diseases World Summit, Boston, MA.

•                2008 Invited participant, Case Western Univ. School of Medicine, Transdisciplinary Research on Energetics and Cancer (TREC)

•                2008 Invited Participant Discussion: PARP-1 Inhibitors for Glioma, Breast, & Ovarian Cancer

•                2005 R21. Secondhand Smoke and Cardiovascular Disease in Zebrafish, R21ES01817

•                2008 Executive Editor, Current Pharmaceutical Design: Nicotinamide Adenine Dinucleotide Biology and Disease

•                2008 Nominated Honorary Editorial Board of The Journal of International Tryptophan Research

•                2007 Nominated to Marquis Who’s Who in America

•                2004-2007 Biomedical Research Technology Transfer Award BRTT. $120,000/yr

•                2004-2007 Genome Science Millennium Fund

•                2000-2003 F32, Individual National Research Service Award. Neuronal and Hematopoietic Gene Regulation of GATA-2. NIH F32HD401940.

•                1999-2000 Post-doctoral Training Grant. Pathobiology of Digestive Diseases. NIH NIDDK DK07542.

 

PRESENTATIONS & MEETINGS

•       Invited presentation, Mayo Clinic, May 2009, “NAD-Centric Pharmacologic Approaches & Obesity/ COPD Animal Modeling Using Zebrafish”

•       Invited presentation and Travel Award, 4^th Annual Metabolic Diseases World Summit, Boston, MA 2008: “A high throughput live transparent animal bioassay to identify non-toxic small molecules or genes that regulate vertebrate fat metabolism for obesity drug development”

•.    Invited panelist, PARP-1 inhibitors for use in melanoma, ovarian cancer, and glioma; Panel Intelligence, LLC

•       Invited speaker, Case Western TREC Retreat 2008, “NAD Pharmacotherapeutics: Zebrafish-based Small Molecule Studies of Lipid Metabolism with Implications for Cancer and Multiple Sclerosis”

•       Invited presentation and Travel Award, PARP 2008, Tucson, AZ

•       Invited speaker, Dept. of Human Nutrition at Ohio State University: “The Zebrafish Genetic Model Organism for Studying Nutrient Function,” Oct. 2007, Columbus, OH

•       Third Annual Ohio Valley Affiliates for Life Sciences, March 7-8, 2007

•       Jones, Kevin S., W. Todd Penberthy. 2006. Poster: “NAD Precursors Prevent Chemically-Elicited Neurodegeneration in Zebrafish Larvae.” East Coast PARP Meeting 2006, Quebec City, Quebec, Canada.

•       7th International Conference on Zebrafish Development and Genetics, June 14-16, 2006, Madison, WI

•       Lin, Shuo and W. Todd Penberthy. 2005. Poster: “Whole-animal Chromatin Immunoprecipitation Using Zebrafish Embryos”. Strategic Conference of Zebrafish Investigators. Principle investigators only and by invitation, Bar Harbor, ME

•       W. Todd Penberthy, Jason R. Jessen, Zhongan Yang, & Shuo Lin. 2002. Oral Presentation: “A Role for BarHl1 in the Regulation of GATA-2 Neural Expression”. The 6^th International Conference on Zebrafish Development and Genetics, Madison, WI

 

SELECTED PUBLICATIONS (from 2009 to present, only)

•       Submissions for a major biotechnology company: Biomaterials, British Medical Journal, and Nanomedicine, (2020)

•       Penberthy, W. Todd and James B. Kirkland. Niacin (2020) in Present Knowledge in Nutrition. 11^th ed., Elsevier, St. Louis, Mo. Edited by Diane Birt and Allison Worden.

•       Penberthy, W. Todd, Mahrou Sadri and Janos Zempleni. Biotin (2020) in Present Knowledge in Nutrition. 11^th ed., Elsevier, St. Louis, Mo. Edited by Diane Birt and Allison Worden.

•       Penberthy, W. Todd. Niacin, Riboflavin, and Thiamine (2019) in Biochemical, Physiological, and Molecular Aspects of Human Nutrition. 4^th ed., Elsevier, St. Louis, Mo. Edited by Marie A. Caudill and Martha H. Stipanuk.

•       Hu, L, K. Ibrahim, M. Stucki, M. Frapolli, N. Shahbeck, F. A. Chaudhry, B. Gorg, D. Haussinger, W. Todd Penberthy, T. Ben-Omran, and J. Haberle (2015). Secondary NAD+ Deficiency in the Inherited Defect of Glutamine Synthase. Journal of Inherited Metabolic Disease. 38(6):1075-83.

•       W. Todd Penberthy & Robert Smith (2015). The Vitamin Cure for Arthritis. A book for laypersons about nutritional approaches to treating arthritis. p1-237.

•       Penberthy, W. Todd and James B. Kirkland. Niacin (2012) in Present Knowledge in Nutrition. 10^th ed., Elsevier, St. Louis, Mo. Edited by Diane Birt.

•       Penberthy, W. Todd. Niacin, Riboflavin, and Thiamine (2012) in Biochemical, Physiological, and Molecular Aspects of Human Nutrition. 3^rd ed., Elsevier, St. Louis, Mo. Edited by John W. Erdman and Ian Macdonald.

•       Penberthy, W. Todd, Soumya C. Chari, Amy Cole, Alexander Cole (2010). Retrocyclins and Activity against HIV-1. Cellular and Molecular Life Sciences 68(13): 2231-2242.

•       Babak Baban, W. Todd Penberthy & Mahmood S. Mozaffari (2010). The Potential Role of Indoleamine 2,3 Dioxygenase (IDO) as a Predictive and Therapeutic Target for Diabetes Treatment: a Mythical Truth; EPMA Journal 1:46–55.

•       Penberthy, W. Todd (2009). Nicotinic Acid-Mediated Activation of Both Membrane and Nuclear Receptors Towards Therapeutic Glucocorticoid Mimetics for Potential Treatment of Multiple Sclerosis; PPAR Research 853707-.

•       Penberthy, W. Todd (guest executive editor) Current Pharmaceutical Design, 2009. Developed theme, coordinated authors / reviewers, and provided oversight to completion. Theme: NAD Biology in Disease.

•       Penberthy, W. Todd & Tsunoda, I. (2009). The Importance of NAD in Multiple Sclerosis. Current Pharmaceutical Design. 2009; 15(1): 64-99.

•       Penberthy, W. Todd (2009). Nicotinamide Biology and Disease. Current Pharmaceutical Design;15(1): 1-2.

 

INVITED JOURNAL REVIEWER

• Diabetes                               

• PPAR Research                   

• Development

• Developmental Dynamics   

• Immunology Letters            

• Molecular Biology Reports

• Antiviral Research              

• Brain Research Bulletin      

• Schizophrenia Research

• Journal of Nutrition             

• Nucleic Acid Research        

• Mutation Research

 

 

Pubmed publications